Grape Seed Extract

GRAPE SEED EXTRACT (GRAPE) INTERACTIONS

* Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with GRAPE

Some medications are changed and broken down by the liver.

Grape juice might increase how quickly the liver breaks down some medications. Taking grape along with some medications that are changed by the liver can decrease the effectiveness of some medications. Before taking grape talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.

* Phenacetin interacts with GRAPE

The body breaks down phenacetin to get rid of it. Drinking grape juice might increase how quickly the body breaks down phenacetin. Taking phenacetin along with grape juice might decrease the effectiveness of phenacetin.

* Warfarin (Coumadin) interacts with GRAPE

Warfarin (Coumadin) is used to slow blood clotting. Grape seed might also slow blood clotting. Taking grape seed along with warfarin (Coumadin) might increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.

Conditions and illness related to grape seed extract

ConConditions & Treatments Related to Grape Seed Extract (GRAPEditions & Treatments Related to * Varicose veins Treatments

* High blood pressure Treatments

* Allergic rhinitis (hayfever) Treatments

* Allergies Treatments

* Allergy Treatments

* Cardiovascular disease Treatments

* Chronic venous insufficiency Treatments

* Hayfever Treatments

* Hypertension Treatments

* Isolated systolic hypertension Treatments

* Night vision Treatments

* Ocular stress Treatments

* Stress Treatments

* Venous insufficiency Treatments

GRAPE

Other Names:

Activin, Black Grape Raisins, Calzin, Draksha, Enocianina, European Wine Grape, Extrait de Feuille de Raisin, Extrait de Feuille de Vigne Rouge, Extrait de Peau de Raisin, Extrait de Pepins de Raisin, Feuille de Raisin, Feuille de Vigne Rouge, Feuille de Vigne Rouge AS 195, Flame Grape, Flame Raisins, Flame Seedless, Folia Vitis Viniferae, Grape Fruit, Grape Fruit Skin, Grape Juice, Grape Leaf, Grape Leaf Extract, Grape Seed, Grape Seed Extract, Grape Seed Oil, Grape Skin, Grape Skin Extract, Grapes, Grapeseed, Huile de Pépins de Raisin, Kali Draksha, Leucoanthocyanin, Muscat, Muskat, Oligomères Procyanidoliques, Oligomeric Proanthocyanidins, Oligomeric Procyanidins, OPC, OPCs, PCO, PCOs, Peau de Raisin, Pépin de Raisin, Petite Sirah, Proanthocyanidines Oligomériques, Proanthodyn, Proanthodyne, Procyanidines Oligomériques, Procyanidolic Oligomers, Purple Grape, Raisin, Raisin Blanc, Raisin de Table, Raisin de Vigne, Raisins, Raisins Noirs, Red Globe, Red Grape, Red Malaga, Red Vine Leaf AS 195, Red Vine Leaf Extract, Sultanas, Table Grapes, Thompson Seedless, Uva, Vitis vinifera, White Grape, Wine Grape, Wine Grapes.

GRAPE SEED EXTRACT (GRAPE) OVERVIEW INFORMATION

Grapes are the fruit of a vine (Vitis vinifera). The whole fruit, skin, leaves and seed of the grape plant are used as medicine. Grape seeds are by-products of the manufacturing of wine. Be careful not to confuse grape with grapefruit, and other similar sounding medicines.

Grape is used for preventing diseases of the heart and blood vessels, varicose veins, hemorrhoids, "hardening of the arteries" (atherosclerosis), high blood pressure, swelling after injury or surgery, heart attack, and stroke.

Some people also use grape as a mild laxative for constipation. You have probably heard of grape "fasts" as part of "detoxification."

Grape seed is used for diabetes complications such as nerve and eye problems, improving wound healing, preventing tooth decay, preventing cancer, an eye disease called age-related macular degeneration (AMD), poor night vision, liver disorders, and hay fever.

Dried grapes, raisins, or sultanas (white raisins) are used for cough.

Grape leaf is used for attention deficit-hyperactivity disorder (ADHD), chronic fatigue syndrome (CFS), diarrhea, heavy menstrual bleeding, uterine bleeding, and canker sores.

Grape leaf is used as a food, particularly in Greek cooking.

How does it work?

Grape contains flavonoids, which can have antioxidant effects, lower the levels of low density lipoproteins (LDLs, or "bad cholesterol"), relax blood vessels, and reduce the risk of coronary heart disease. The antioxidants in grape might help to prevent heart disease and have other potentially beneficial effects. Red grape varieties provide more antioxidants than white or blush grape varieties.

Grape leaf might reduce inflammation and have astringent effects. In other words, grape leaf seems to be able to draw tissue together, which could help stop bleeding and diarrhea. These properties appear to be greatest in the red leaves.

GRAPE SEED EXTRACT (GRAPE) USES &